Antifragility implies more to gain than to lose, equals more upside than downside, equals (favorable) asymmetry.
The barbell strategy (or bimodal strategy): Never go for the median. Always go with two extremes to remove downside. For example with weight lifting: Heavy lifts and long effortless walks instead of going hard sometimes and walking at a decent pace with incline.
The strength of the computer entrepreneur Steve Jobs was precisely in distrusting market research and focus groups - those based on asking people what they want - and following his own imagination. His modus was that people don't know what they want until you provide them with it.